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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
33.33
Human Site:
S356
Identified Species:
52.38
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
S356
H
G
Y
F
L
N
P
S
R
S
S
P
Q
E
I
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
S356
H
G
Y
F
L
N
P
S
R
S
S
P
Q
E
I
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
S356
H
G
Y
F
L
N
P
S
R
S
S
P
Q
E
I
Dog
Lupus familis
XP_850081
1066
122542
S356
H
G
Y
F
L
N
P
S
R
S
S
P
Q
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
A418
Y
F
K
Y
P
L
M
A
L
G
E
L
C
E
T
Rat
Rattus norvegicus
Q6P7A2
1066
122361
S356
H
G
F
F
L
N
P
S
R
S
S
P
Q
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
S357
H
G
Y
F
L
N
P
S
R
S
S
P
Q
E
I
Frog
Xenopus laevis
NP_001084506
1072
122544
S355
H
G
Y
F
I
N
P
S
R
S
S
P
Q
E
I
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
S361
H
G
F
F
L
N
P
S
R
S
S
P
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
I333
R
G
H
L
W
S
S
I
N
A
S
L
E
Q
T
Honey Bee
Apis mellifera
XP_393070
965
109934
H312
K
C
S
S
E
V
R
H
L
T
L
Q
W
I
G
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
I327
Y
F
Q
R
M
D
P
I
R
T
M
L
H
Q
L
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
S325
F
E
K
P
S
R
T
S
G
R
D
H
Q
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
N369
A
S
S
G
M
F
V
N
L
S
A
V
M
L
R
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
S308
P
P
F
K
E
L
S
S
N
G
F
M
S
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
6.6
93.3
N.A.
N.A.
100
93.3
86.6
N.A.
13.3
0
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
N.A.
100
100
100
N.A.
46.6
6.6
53.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
7
0
7
7
0
0
7
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
7
0
0
14
0
0
0
0
0
7
0
7
60
0
% E
% Phe:
7
14
20
54
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
60
0
7
0
0
0
0
7
14
0
0
0
0
7
% G
% His:
54
0
7
0
0
0
0
7
0
0
0
7
7
0
0
% H
% Ile:
0
0
0
0
7
0
0
14
0
0
0
0
0
7
54
% I
% Lys:
7
0
14
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
47
14
0
0
20
0
7
20
0
7
14
% L
% Met:
0
0
0
0
14
0
7
0
0
0
7
7
7
0
0
% M
% Asn:
0
0
0
0
0
54
0
7
14
0
0
0
0
7
0
% N
% Pro:
7
7
0
7
7
0
60
0
0
0
0
54
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
60
14
0
% Q
% Arg:
7
0
0
7
0
7
7
0
60
7
0
0
0
0
7
% R
% Ser:
0
7
14
7
7
7
14
67
0
60
60
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
14
0
0
0
0
20
% T
% Val:
0
0
0
0
0
7
7
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
14
0
40
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _